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To view the latest research studies, visit the new Infonet. This page has not been updated since Jan. 31, 2011.

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The following research studies currently are recruiting participants:


The Center for Family Planning Research is conducting a research study to better understand how birth control affects the immune system of the uterus. You may be eligible to participate if you want to use an IUD for contraception and are 18 to 40 years of age with regular periods, in good health, not currently pregnant or breastfeeding, and not currently using hormones for birth control. Participants will receive up to $300 upon completion of the study. The study involves two visits to Magee-Womens Hospital of UPMC over the course of two months. For more information, contact the Center for Family Planning Research at 412-641-5496 and ask for the CHIC study. (Posted 01/19/11)


Is your child sad, tearful, grumpy, or cranky? A new research study is recruiting children ages 7 to 12 with a depressive disorder. Eligible participants will be randomly assigned to one of two talk therapies that treat childhood depression. Psychotherapy is free of charge and offered for six months. At the conclusion of treatment, parents and children will be asked to participate in additional interviews over the span of one year. Compensation will be provided for all interviews. To see if your child qualifies, contact Patrick McElfresh at 412-246-5700.
(Posted 01/19/11)


Do you have schizophrenia or schizoaffective disorder and use marijuana? If so, a new research study at the University of Pittsburgh may be able to help with motivation, concentration, getting along with others, succeeding at school or work, organizing and planning, and managing stress. Eligible participants must be between the ages of 18 and 55, have schizophrenia or schizoaffective disorder, use marijuana, and are able to regularly visit the University of Pittsburgh. Participation in this research-based program is at no cost to the participant. Eligible participants may be selected to receive a new non-drug treatment for individuals with schizophrenia or schizoaffective disorder who use marijuana. This treatment is based upon a previous program known as cognitive enhancement therapy. Involvement in this study will help researchers determine whether this experimental intervention will benefit those with this condition. Eligible participants will be compensated for any research assessments. For more information, contact Amber Bahorik at 412-864-3807.
(Posted 01/19/11)


Do you have asthma? The University of Pittsburgh Asthma Institute and the University of Pittsburgh School of Medicine are looking for men and women volunteers between the ages of 18 and 65, in good health, and with a moderate to severe diagnosis of asthma, to participate in a research study involving an investigational drug. Volunteers must be nonsmokers with less than a 10 pack year history and currently use an inhaled steroid such as Flovent, Pulmicort, Advair, Symbicort, or QVAR. The study includes 13, two-hour visits to UPMC Montefiore over 22 weeks, a study-related physical examination, pulmonary function tests, and blood draws. If qualified, participants will be compensated for time and travel to each visit. For more information, contact the Asthma Institute at 1-866-804-5278.  (Posted 01/19/11)


Healthy, premenopausal women ages 25 to 49 whose mother or sister had breast cancer (or not) are needed as participants in a research study at the University of Pittsburgh to help researchers understand the effects of stress in everyday life. Participants must work full time during the day, do not smoke, or take medication other than birth control. For more information about the Women’s Stress Response study, call 412-641-7532 or e-mail belinsc2@upmc.edu.  (Posted 01/19/11)


Female volunteers are needed for a contraceptive patch study. You may be eligible to participate if you are 18 to 44 years old, in general good health, have regular periods, are willing to abstain from sexual activity, are sexually active and willing to use condoms, are surgically sterilized, or are with one partner who has had a vasectomy, and willing to visit Magee-Womens Hospital of UPMC for at least 25 visits over the course of four months. Reimbursement is provided for time and travel. For more information, contact the Center for Family Planning Research at 412-641-5496 or visit http://mwrif.org/120/. (Posted 01/19/11)


Thinking of quitting smoking? UPMC seeks smokers ages 18 to 65 who plan to quit smoking to participate in a nine-week research study on the short-term effects of two oral medications on smoking behavior, craving, and mood. One medication, Zyban (bupropion), is FDA-approved for smoking cessation. The other medication, Provigil (modafinil), is FDA-approved for wakefulness. This is not a treatment study. Participants will be asked to take study medication that may or may not contain active components. Compensation will be provided. Participants who complete the study will be offered optional brief counseling and Zyban at no cost after the study is over to help in quitting smoking permanently. For more information, call 412-246-5306 or visit http://www.smokingstudies.pitt.edu/. (Posted 01/19/11)


University of Pittsburgh researchers are conducting a new research study involving patients with diabetes. This study will test a new device that measures blood sugar values on the skin and compares it to traditional methods such as glucose monitors. The study includes three visits at UPMC Montefiore in the morning. Compensation up to $200 and parking provided. To participate, please call the study coordinator at 412-647-6799. (Posted 01/19/11)


Researchers at UPMC are looking for healthy men and women ages 35 to 60 years old to participate in a research study about how the brain changes with change in blood pressure. Participants must not have hypertension, heart or blood vessel disease, insulin dependent diabetes, or a chronic medical, physical, or psychiatric disease requiring medication Participants will attend three sessions in one month’s time. Each sessions lasts approximately two hours. One session will include an MRI. Payment at the completion of the study will be $150. Some participants will be asked to repeat these sessions in approximately two years. For more information, call Kim Novak at 412-246-6200. (Posted 01/19/11)


Researchers at the University of Pittsburgh are recruiting participants for a study to learn about depression in mothers and how it affects their children. The study will test the effectiveness of an experimental talk therapy intervention for mothers who suffer from depression. To be eligible, you must be a mother, age 18 or older, who is currently experiencing distress and hopelessness. You must also have a child, age 7 to 17, who is currently being treated for a psychiatric disorder. The study includes nine sessions of experimental talk therapy over the course of three months. Follow-up assessments will occur every three months over the course of one year. The total time of participation for this study is one year. All psychological assessments and experimental talk therapy sessions will be provided at no cost. You and your child will be compensated for completing assessments. For more information, contact the Depression and Manic Depression Prevention Program at 412-246-5588. (Posted 01/19/11)


UPMC seeks healthy adolescents ages 12 to 17 to participate in a study of physical illness and mood. To be eligible your child must have no history of medical or psychiatric problems. Your child will be asked to complete an interview, a blood draw, and an fMRI, which is a noninvasive procedure that uses magnetic waves to take images of the brain. These procedures will be conducted twice, once at enrollment and again three months later. Your child will be compensated for participation. For more information call 412-692-8635. (Posted 01/19/11)


Want to lose weight? Having hot flashes? A new University of Pittsburgh study is recruiting women with hot flashes for a research study using weight loss interventions to manage menopausal hot flashes. You may qualify if you are 40 to 65 years old, have not had a menstrual period in the past three months, are having daily hot flashes, are interested in losing weight, and are not taking medications or supplements for hot flashes. Study procedures include a telephone and in-person interview and a six-month weight loss program. Laboratory procedures take place at UPMC in Oakland, and monitoring occurs at your home or workplace. Participants receive $50 for completing study procedures and reimbursement for parking. For more information, call 412-648-9186. (Posted 01/19/11)


Children's Hospital of Pittsburgh of UPMC is conducting a study to understand why some children are more at risk for obesity and diabetes. Healthy children ages eight to 17 are eligible. The study involves an initial eligibility visit to Children's Hospital, similar to a routine doctor's visit. The study involves body composition evaluation and blood and breathing testing. Compensation will be provided. Call 412-692-8721 for more information. (Posted 01/06/11)


UPMC is conducting a research study on how the brain develops. Children and teens ages nine and up, who have not had a brain injury or psychiatric disorder, are eligible. The study involves paper and pencil tests, computer games, and an MRI. The study is done in two three-hour sessions, and participants will receive $50 to $100 for completion of the study. For more information, contact lunalncd@gmail.com or 412-383-8180. (Posted 01/03/11)


Researchers at the University of Pittsburgh School of Medicine are seeking older adults ages 60 or above who currently are experiencing symptoms of depression. Symptoms of depression can include: feeling hopeless, pessimistic; loss of interest or pleasure in things you once enjoyed; insomnia, early-morning awakening or oversleeping; appetite and/or weight loss, overeating or weight gain; thoughts of death or suicide; difficulty concentrating, remembering or making decisions; persistent physical symptoms such as headaches, chronic pain or digestive disorders. The goal of the study is to examine better ways to treat difficult depression in older adults. Participation in the study lasts between three and 10 months. Clinical visits, study medication, and medical evaluations will be provided at no cost for eligible participants. For more information, call 412-246-6006 between the hours of 8:30 a.m. and 4:30 p.m. (Posted 01/03/11)


Is your son or daughter overweight and between the ages of 12 and 18? If so, he or she may be eligible to participate in a research study at Children's Hospital of Pittsburgh of UPMC examining the effect of exercise on risk factors for diabetes. To be eligible for this study, he or she must be sedentary (no structured physical activity) and not on a daily medication. The study involves physical exams, body composition and fitness evaluation, blood testing, overnight stays, and exercise training or nutrition counseling. Compensation is provided for participation: females can receive up to $445 and males up to $545. Call Sarah at 412-692-8199 for more information. (Posted 12/13/10)


Researchers at Western Psychiatric Institute and Clinic are conducting a research study to better understand how the brain functioning of individuals with insomnia compares to individuals without insomnia. We are currently recruiting healthy controls. The study involves questionnaires, a physical exam, evaluation of sleep patterns in the sleep laboratory, and brain imaging studies. Participants should be 18 to 50 years old and without sleep problems, in good physical and emotional health, and not currently taking medication for anxiety or depression. Compensation will be provided upon completion of the study. To learn more, call 412-246-6400 or e-mail chakanzn@upmc.edu. (Posted 12/13/10)


UPMC is conducting a treatment study for bulimia nervosa. Eligible individuals will receive cognitive-behavioral therapy (CBT), the treatment of choice for bulimia, and will be assigned by chance to receive treatment in face-to-face groups or experimental,Internet-delivered chat groups. There is no cost for participating in this trial. If you are 18 years or older and have internet access, you may be eligible. Contact the CBT4BN Research Coordinator at 412-647-1776 or cbt4bn@upmc.edu for more information. (Posted 12/13/10)


Do you have a child between ages nine and 17 who seems sad, depressed, and irritable most of the time? Has your child lost interest in things he or she used to enjoy? Researchers at the University of Pittsburgh are looking for children and teens with depression to participate in a study of social and emotional development. Participation involves computer tasks, an MRI scan to measure brain activity, and questionnaires and interviews about behaviors, feelings, and daily experiences. Compensation is provided. For more information, and to see if your child qualifies to participate in this study, call 412-383-5425. (Posted 12/6/10)


Have you had a baby recently? Feeling sad, down, or overwhelmed? Researchers at UPMC are studying whether depression after childbirth can be treated with the hormone estrogen. One in seven women experiences depression in the three months following the birth of a baby. Women 18 to 45 years old, who have had a baby in the past three months, and are experiencing depression or lasting sadness, can participate.  As part of the study, the participants will have contact with study staff in person or by telephone for eight weeks. Also, they will be randomly assigned to take one of three study medications: estradiol patch, Zoloft®, or placebo. Participants may receive up to $315 for completing the study. Child care is offered during visits and parking or bus fare is provided. For more information, call toll-free 1-800-436-2461 or visit http://womensbehavioralhealth.org/. (Posted 11/29/10)


Have you been diagnosed with type 2 diabetes and have trouble sleeping at night? Researchers at the University of Pittsburgh are looking at whether sleepiness affects the amount of physical activity in people with type 2 diabetes. You may be eligible if you are age 30 years and older; willing to spend two or three nights at the sleep center in Oakland; have been diagnosed with sleep apnea at the start of the study and have never been on previous treatment (CPAP); willing to be randomized to either a standard device for sleep apnea or a similar mock device that has no benefits; and are on oral medication and/or diet treatment for diabetes (not insulin). Participants will wear an activity monitor and a continuous glucose monitor. Participants randomized to the mock device will be offered to repeat the study with the sleep apnea treatment device. Eligible participants can receive up to $320 (or up to $485 if repeating the study) as reimbursement for participation. For more information, call 412-624-3597 or e-mail mli9@pitt.edu. (Posted 11/29/10)


To learn more about various research studies and clinical trials at the University of Pittsburgh, visit the Office of Clinical Research website at www.clinicalresearch.pitt.edu.